Synthesis of hydroacridines and 1,8-dioxooctahydroxanthenes using primary amino alcohols as reagent or catalysis via three-component condensation reactions


Mohamed S. K., Abdelhamid A., Maharramov A., Xəlilov Ə., Gurbanov A. V., Allahverdiyev M.

Journal of Chemical and Pharmaceutical Research, vol.4, no.2, pp.955-965, 2012 (Scopus) identifier

  • Nəşrin Növü: Article / Article
  • Cild: 4 Say: 2
  • Nəşr tarixi: 2012
  • jurnalın adı: Journal of Chemical and Pharmaceutical Research
  • Jurnalın baxıldığı indekslər: Scopus
  • Səhifə sayı: pp.955-965
  • Açar sözlər: Amino alcohols, Hydracridinones and hydroxanthenone, Three component reactions, β-diketone
  • Adres: Bəli

Qısa məlumat

Two major classes of compounds of hydroacridinones and hydroxanthenones have been synthesized in a satisfactory yield via three component condensation reaction of amino alcohols, dimedone and aromatic aldehydes. The applied amino alcohols acted as reactant in one reaction to afford 3,6,6-tetramethyl-,2,3,4,5,6,7,8,9,10-decahydroacridine- 1,8-diones and acted as catalyst in the other reaction to afford 1,8-dioxooctahydroxanthenones. The structure of products has been characterized by X-ray crystal structural analyses, 13C-NMR, 1H-NMR, IR and Mass spectra.