Desulfitative direct (hetero)arylation of C(heteroaryl)-H bonds using (hetero)aryl sulfonyl chlorides as coupling partners: A review

Rzayev R., Khalilov A.

Chemical Review and Letters, vol.7, no.3, pp.479-490, 2024 (Scopus) identifier

  • Publication Type: Article / Review
  • Volume: 7 Issue: 3
  • Publication Date: 2024
  • Doi Number: 10.22034/crl.2024.465900.1371
  • Journal Name: Chemical Review and Letters
  • Journal Indexes: Scopus
  • Page Numbers: pp.479-490
  • Keywords: (hetero)aryl-substituted heteroarenes, aryl sulfonyl chlorides, C-H arylation, Desulfitative cross-coupling reactions, palladium
  • Azerbaijan State University of Economics (UNEC) Affiliated: Yes

Abstract

This review is an update on development of methodologies towards the synthesis of (hetero)aryl-substituted heteroarenes through desulfitative direct arylation of C(heteroaryl)-H bonds using aryl sulfonyl chlorides as coupling partners starting from 2011 onwards. For clarity, the review is divided into four main sections according to the type of heterocycles: (i) arylation of nitrogen-heterocycles; (ii) arylation of oxygen-heterocycles; (iii) arylation of sulfur-heterocycles; and (iv) arylation of heterocycles with two heteroatoms.