ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.74, pp.1599-1604, 2018 (ESCI)
The title molecule, C18H16F3NO7, comprises a fused cyclic system containing four five-membered (two dihydrofuran and two tetrahydrofuran) rings and one six-membered (piperidine) ring. The five-membered dihydrofuran and tetrahydrofuran rings adopt envelope conformations, and the six-membered piperidine ring adopts a distorted chair conformation. Intramolecular O center dot center dot center dot F interactions help to stabilize the conformational arrangement. In the crystal structure, molecules are linked by weak C-H center dot center dot center dot O and C-H center dot center dot center dot F hydrogen bonds, forming a three-dimensional network. The Hirshfeld surface analysis confirms the dominant role of H center dot center dot center dot H contacts in establishing the packing.