Recent advances in the synthesis of trifluoromethyl ethers through the direct O-trifluoromethylation of alcohols

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Rzayev R., Niyazova A., Hüseynov M., Musayeva V., Razzaq H. M.

Chemical Review and Letters, vol.7, no.8, pp.742-753, 2024 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 8
  • Publication Date: 2024
  • Doi Number: 10.22034/crl.2024.470142.1391
  • Journal Name: Chemical Review and Letters
  • Journal Indexes: Scopus
  • Page Numbers: pp.742-753
  • Keywords: alcohols, Organofluorine compounds, oxidative O-functionalization, trifluoromethyl ethers, trifluoromethylation
  • Open Archive Collection: Article, Digital Heritage Collection
  • Azerbaijan State University of Economics (UNEC) Affiliated: Yes

Abstract

In this review, the pivotal achievements and recent advances on direct O-trifluoromethylation of alcohols reported up to 2024 are retrospectively considered and their potency for synthesis of useful trifluoromethyl ethers is demonstrated. The reported data are organized according to main types of catalytic systems (i.e., metal-catalyzed/mediated, electro-catalyzed, base-mediated, and catalyst-free O-trifluoromethylations).