Oral delivery of proteins and peptides by mucoadhesive nanoparticles

Sharifi S., Samani A. A., Ahmədian E., Eftekhari A., Derakhshankhah H., Jafari S., ...daha çox

Biointerface Research in Applied Chemistry, vol.9, no.2, pp.3849-3852, 2019 (Scopus) identifier

  • Nəşrin Növü: Article / Article
  • Cild: 9 Say: 2
  • Nəşr tarixi: 2019
  • Doi nömrəsi: 10.33263/briac92.849852
  • jurnalın adı: Biointerface Research in Applied Chemistry
  • Jurnalın baxıldığı indekslər: Scopus
  • Səhifə sayı: pp.3849-3852
  • Açar sözlər: Mucoadhesive nanoparticles, Nanotechnology, Oral delivery
  • Açıq Arxiv Kolleksiyası: Məqalə
  • Adres: Bəli

Qısa məlumat

It seems that an ever growing tendency is necessary for the development of a strategy that can not only protect the peptides and proteins from degradation by the enzymes but also can improve their absorption without affecting biological activity. Delivery of peptides and proteins into the oral cavity remains an interesting approach, however for its availability some distinctive problems should be addressed. A wide variety of carriers have been investigated for delivery of peptides and proteins for the protection of their formulation and structure against the enzymatic environment of the gastrointestinal tract.