Preparation of magnetic nanodendrimers and their applications in organic reactions and biomedicine: An update
Chemical Review and Letters, vol.8, no.2, pp.211-239, 2025 (Scopus)
- Publication Type: Article / Review
- Volume: 8 Issue: 2
- Publication Date: 2025
- Doi Number: 10.22034/crl.2024.464729.1364
- Journal Name: Chemical Review and Letters
- Journal Indexes: Scopus
- Page Numbers: pp.211-239
- Keywords: Biomedicine, Dendrimer, Generation dendrimer, MNPs, PAMAM
- Open Archive Collection: Article, Review
- Azerbaijan State University of Economics (UNEC) Affiliated: Yes
Abstract
In this review, the bioactive agents can be encapsulated into the interior of the dendrimers or chemically grafted/physically adsorbed on the dendrimer surface with the option of tailoring the carrier to the fundamental needs of the active material and its therapeutic applications. However, the high density of exo-presented surface groups allowed attachment of targeting groups or functionality that could modify the solution behavior or toxicity of dendrimers. Quite remarkably, modified dendrimers were shown to act as nano-drugs against tumors, bacteria, and viruses. Also, it was applied in medicin and agents of contrast for MRI.